HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1,1,4,4,4-Hexafluoro-2,3-butanedione → Ethyl 3-amino-5,6-bis(trifluoromethyl)pyrazine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1,1,4,4,4-Hexafluoro-2,3-butanedione | HCID 2759264 | — |
| Reactant | HCID 12439913 | HCID 12439913 | — |
| Product | Ethyl 3-amino-5,6-bis(trifluoromethyl)pyrazine-2-carboxylate | HCID 86657667 | — |
Reaction Steps
The title compound was prepared from amino-carbamimidoyl-acetic acid ethyl ester (Intermediate B2) and 1,1,1,4,4,4-hexafluorobutane-2,3-dione analogously to Intermediate B; 10 LCMS Rt=4.72 minutes, [M+H]+ 304.2/326.1 Method 10 minLC_v002.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08476269B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-f5e69e152b1640d19dcd3ad827dc6d67 |
| Source note | uspto-grants-2013_07 |