反应详情

A solution of tert-butyl ((5-(4-((3-fluorobenzyl)oxy)phenyl)-1,3,4-thiadiazol-2-yl)methyl)carbamate, dioxane (16 mL), and 4N HCl in dioxane (13 ml) was stirred at room temperature for 4 h. The resulting mixture was concentrated in vacuo to yield (5-(4-((3-fluorobenzyl)oxy)phenyl)-1,3,4-thiadiazol-2-yl)methanamine, which was in the next step used directly without further purification. MS (ES+) 316 (MH+).

1. concentrationThe resulting mixture was concentrated in vacuo