Sulfuryl chloride → HCID 69443055, compound

HRID 446164Notes

Reaction equation

HRID 446164 reaction equation
S(Cl)([Cl:4])(=O)=O.[CH2:6]([O:13][C:14]1[CH:24]=[CH:23][C:17]2[CH:18]=[C:19]([CH2:21]O)[S:20][C:16]=2[CH:15]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>ClCCl>[CH2:6]([O:13][C:14]1[CH:24]=[CH:23][C:17]2[CH:18]=[C:19]([CH2:21][Cl:4])[S:20][C:16]=2[CH:15]=1)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 69442579HCID 69442579, compound

Product 1

HCID 69443055HCID 69443055, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Sulfonyl chloride (20 ml) is added to a solution of (6-benzyloxy-benzothien-2-yl) methanol (4.20 g, 15.50 mmol) in dichloromethane (40 ml). The mixture was maintained at reflux for 2 h, cooled at room temperature then concentrated under vacuum to give 4.20 g as an oil.

Workup

  1. temperatureThe mixture was maintained
  2. temperatureat reflux for 2 h
  3. concentrationthen concentrated under vacuum
  4. customto give 4.20 g as an oil

Sources & evidence

ORD record
ord-5e381fb8841e4570a4c562b3ab8b372d
Source dataset
uspto-grants-2013_07
Patent number
US08476455B2

Reaction notes

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