(-)-Menthol → Menthol

HRID 446208Notes

Reaction equation

HRID 446208 reaction equation
O[C@H](C)CC(OC1(C)CCC(C(C)C)CC1)=O.[CH3:18][C@H:19]1[CH2:24][C@@H:23]([OH:25])[C@H:22]([CH:26]([CH3:28])[CH3:27])[CH2:21][CH2:20]1>>[CH:19]1([CH3:18])[CH2:20][CH2:21][CH:22]([CH:26]([CH3:27])[CH3:28])[CH:23]([OH:25])[CH2:24]1

Participants

3

Reactant 2

HCID 16666(-)-Menthol2×HCID 86647225HCID 86647225, compound

Product 1

HCID 1254Menthol

Procedure

A sensate composition was prepared by mixing the (3R)-1-menthyl 3-hydroxybutyrate obtained in Example 1 with 1-menthol at a ratio of 1:9 (weight ratio). Oral sensory evaluation was carried out by preparing 1,000 ml of a 20 ppm aqueous solution of the thus obtained sensate composition, and the oral sensory evaluation was carried out also on a 20 ppm aqueous solution of 1-menthol alone as a comparison.

Workup

  1. customA sensate composition was prepared
  2. customOral sensory evaluation was carried out by preparing 1,000 ml of a 20 ppm aqueous solution of the thus obtained sensate composition

Sources & evidence

ORD record
ord-394fdecb274948d6aa395aa5819f86d4
Source dataset
uspto-grants-2013_07
Patent number
US08476472B2

Reaction notes

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