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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 446391Generated: October 26, 2026

3-(3-(Hydroxymethyl)phenyl)propan-1-ol → 3-(4-(tert-Butyldimethylsilyloxy)butyl)benzaldehyde

https://huagongshe.com/reaction/446391

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-(Hydroxymethyl)phenyl)propan-1-olHCID 55267680—
Reactant(3-(4-(tert-Butyldimethylsilyloxy)butyl)phenyl)methanolHCID 58168515—
Product3-(4-(tert-Butyldimethylsilyloxy)butyl)benzaldehydeHCID 58168615—

Reaction Steps

Prepared by the method of Aromatic Intermediate 18, step c using (3-(4-(tert-butyldimethylsilyloxy)butyl)phenyl)methanol [Aromatic Intermediate 19, step b] (0.72 g) in place of 3-(3-(hydroxymethyl)phenyl)propan-1-ol. Yield 0.64 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08476265B2
Source datasetuspto-grants-2013_07
ORD IDord-756352e5df8b4b83a9ef1e2fb98c67c7
Source noteuspto-grants-2013_07