Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 446415Generated: October 25, 2026

Isovaleryl chloride → 2-(2-Methylpropyl)-1,3-thiazole-4-carboxylic acid

https://huagongshe.com/reaction/446415

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsovaleryl chlorideHCID 66054—
ReactantEthyl 2-(pentan-3-yl)thiazole-4-carboxylateHCID 57989261—
Product2-(2-Methylpropyl)-1,3-thiazole-4-carboxylic acidHCID 23588154—

Reaction Steps

Prepared by the method of Carboxylic Acid 3, using 3-methylbutanoyl chloride (10 mL) in place of 2-ethylbutanoyl chloride in step a. Yield 3.8 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08476265B2
Source datasetuspto-grants-2013_07
ORD IDord-58dfd9f58bd54577b2fec49daac123de
Source noteuspto-grants-2013_07