huagongshe.com
HRID44654

反应详情

EQUATION

反应方程式

HRID 44654 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CCOCC
HCID3283

Diethyl Ether

C4H10O

结构：CC(C)(C)OC(=O)N[C@H](C(=O)N1CCOCC1)c1ccccc1
HCID57444168

未命名化合物

PRODUCTS

生成物

1
结构：Cl.N[C@H](C(=O)N1CCOCC1)c1ccccc1
HCID45158390

(2S)-2-amino-1-morpholin-4-yl-2-phenylethanone;hydrochloride

C12H17ClN2O2

收率 90%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

2 次

PROCEDURE

实验过程

1.327 g of N-(tert-butoxycarbonyl)-(1S)-2-morpholin-4-yl-2-oxo-1-phenylethylamine was dissolved in 15 mL of dioxane and treated with 3.5 mL of HCl 4 M in dioxane overnight. The solvent was removed and the solid was triturated with diethylether yielding 920 mg of the product (yield 90%).

WORKUP

后处理

  1. customThe solvent was removed