HRID446547

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)CCCCC=O

HCID86761901

未命名化合物

结构：CN(CCCN(C)C(=O)c1ccc(CNCC(C)(C)C)s1)C(=O)OC(C)(C)C

HCID86761908

未命名化合物

PRODUCTS

生成物

结构：CN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)CCCCCN(Cc1ccc(C(=O)N(C)CCCN(C)C(=O)OC(C)(C)C)s1)CC(C)(C)C

HCID66671527

未命名化合物

收率 69%

PROCEDURE

实验过程

The compound (122 mg, 0.307 mol) obtained in Example 55b and the compound (171 mg, 0.368 mmol) obtained in Example 4g were used to give the title compound (181 mg; yield, 69%) as a colorless oily substance according to the method described in Example 45b.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0b1ef76f5778441bbc023b2a979d9b54
来源数据集: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08476253B2
来源说明: uspto-grants-2013_07

反应 SMILES

[CH3:1][C:2]([CH3:28])([CH3:27])[CH2:3][NH:4][CH2:5][C:6]1[S:10][C:9]([C:11]([N:13]([CH3:26])[CH2:14][CH2:15][CH2:16][N:17]([CH3:25])[C:18](=[O:24])[O:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[O:12])=[CH:8][CH:7]=1.[C:29]1([C:57]2[CH:62]=[CH:61][CH:60]=[CH:59][CH:58]=2)[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[NH:35][C:36](=[O:56])[O:37][CH:38]1[CH2:43][CH2:42][N:41]([CH2:44][CH2:45][N:46]([CH3:55])[C:47](=[O:54])[CH2:48][CH2:49][CH2:50][CH2:51][CH:52]=O)[CH2:40][CH2:39]1>>[C:29]1([C:57]2[CH:58]=[CH:59][CH:60]=[CH:61][CH:62]=2)[CH:34]=[CH:33][CH:32]=[CH:31][C:30]=1[NH:35][C:36](=[O:56])[O:37][CH:38]1[CH2:43][CH2:42][N:41]([CH2:44][CH2:45][N:46]([C:47](=[O:54])[CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][N:4]([CH2:5][C:6]2[S:10][C:9]([C:11](=[O:12])[N:13]([CH2:14][CH2:15][CH2:16][N:17]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH3:25])[CH3:26])=[CH:8][CH:7]=2)[CH2:3][C:2]([CH3:28])([CH3:27])[CH3:1])[CH3:55])[CH2:40][CH2:39]1