HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Amino-2-N-Boc-1,2,3,4-tetrahydro-isoquinoline → HCID 86761910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Amino-2-N-Boc-1,2,3,4-tetrahydro-isoquinoline | HCID 2756371 | — |
| Reactant | 1-{2-[Methyl(6-oxohexanoyl)amino]ethyl}piperidin-4-yl biphenyl-2-ylcarbamate | HCID 86761901 | — |
| Product | HCID 86761910 | HCID 86761910 | 19.1% |
Reaction Steps
tert-Butyl 6-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate (227 mg, 0.914 mmol) and the compound (638 mg, 1.37 mmol) obtained in Example 4g were used to give the title compound (122 mg; yield, 19%) as a colorless oily substance according to the method described in Example 45b.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08476253B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-c6d54f89a7574c55943588cd1e7c4452 |
| Source note | uspto-grants-2013_07 |