1-Methylimidazole → HCID 178480822, compound

HRID 446704Notes

Reaction equation

HRID 446704 reaction equation
[CH3:1][N:2]1[CH:6]=[CH:5][N:4]=[CH:3]1.[F:7][C:8]([F:18])([F:17])[C:9]1[CH:16]=[CH:15][C:12]([CH2:13][Br:14])=[CH:11][CH:10]=1>C1(C)C=CC=CC=1>[Br-:14].[F:7][C:8]([F:18])([F:17])[C:9]1[CH:16]=[CH:15][C:12]([CH2:13][N+:4]2[CH:5]=[CH:6][N:2]([CH3:1])[CH:3]=2)=[CH:11][CH:10]=1

Participants

4

Reactant 2

HCID 13901-MethylimidazoleHCID 1230621-(Bromomethyl)-4-(trifluoromethyl)benzene

Product 1

HCID 178480822HCID 178480822, compoundYield 107.4%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

By carrying out the procedure as in Step 1 of Example 10, but starting with 2 g of N-methylimidazole and 8.73 g of 4-trifluoromethylbenzyl bromide, at the reflux temperature of toluene for 2 hours, 8.4 g of 1-(4-trifluoromethylbenzyl)-3-methylimidazolium bromide are obtained in the form of an orange-yellow solid whose characteristics are the following:

Sources & evidence

ORD record
ord-f87c406f94b04f7da68e768f0a3eb234
Source dataset
uspto-grants-2013_07
Patent number
US08481522B2

Reaction notes

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