反应详情

Following the procedure for the preparation of 4-(3-chloro-4-methoxyphenyl)-3-(4-(quinolin-2-ylmethoxy)phenyl)furan-2(5H)-one-using 5-(2-bromoacetyl)-2-methoxybenzonitrile provided the title compound. 1H NMR (500 MHz, d6-DMSO): δ 8.32-8.28 (m, 1H), 8.06-7.95 (m, 2H), 7.81-7.76 (m, 2H), 7.62-7.56 (m, 1H), 7.49-7.39 (m, 2H), 7.26-7.18 (m, 3H), 7.12-7.05 (m, 2H), 5.41 (s, 2H), 5.33 (s, 2H), 3.89 (s, 3H). MS: M+H: m/z=449.0. HPLC: 91%, (Condition-H).