Piperidin-4-ol → HCID 68577393, compound

HRID 446869Notes

Reaction equation

HRID 446869 reaction equation
[Cl:1][C:2]1[CH:31]=[C:30]([F:32])[CH:29]=[CH:28][C:3]=1[O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][S:12]([C:15]1[CH:27]=[CH:26][C:18]([C:19]([NH:21][CH2:22][C:23](O)=[O:24])=[O:20])=[CH:17][CH:16]=1)(=[O:14])=[O:13].[OH:33][CH:34]1[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]1>>[Cl:1][C:2]1[CH:31]=[C:30]([F:32])[CH:29]=[CH:28][C:3]=1[O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][S:12]([C:15]1[CH:16]=[CH:17][C:18]([C:19]([NH:21][CH2:22][C:23]([N:37]2[CH2:38][CH2:39][CH:34]([OH:33])[CH2:35][CH2:36]2)=[O:24])=[O:20])=[CH:26][CH:27]=1)(=[O:14])=[O:13]

Participants

3

Reactant 2

HCID 79341Piperidin-4-olHCID 68492215HCID 68492215, compound

Product 1

HCID 68577393HCID 68577393, compound

Procedure

The title compound was prepared from {4-[2-(2-chloro-4-fluoro-phenoxy)-phenylsulfamoyl]-benzoylamino}-acetic acid and 4-hydroxypiperidine according to the method described in Example 1.1/f. MS (EI) 562.3 (MH+).

Sources & evidence

ORD record
ord-9e8c23d39e79485f951d354ca1626644
Source dataset
uspto-grants-2013_07
Patent number
US08481527B2

Reaction notes

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