Piperidin-4-ol → HCID 68579796, compound

HRID 446878Notes

Reaction equation

HRID 446878 reaction equation
[Br:1][C:2]1[CH:31]=[CH:30][C:5]([O:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[NH:13][S:14]([C:17]2[CH:29]=[CH:28][C:20]([C:21]([NH:23][CH2:24][C:25](O)=[O:26])=[O:22])=[CH:19][CH:18]=2)(=[O:16])=[O:15])=[C:4]([Cl:32])[CH:3]=1.[OH:33][CH:34]1[CH2:39][CH2:38][NH:37][CH2:36][CH2:35]1>>[Br:1][C:2]1[CH:31]=[CH:30][C:5]([O:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[NH:13][S:14]([C:17]2[CH:29]=[CH:28][C:20]([C:21]([NH:23][CH2:24][C:25]([N:37]3[CH2:38][CH2:39][CH:34]([OH:33])[CH2:35][CH2:36]3)=[O:26])=[O:22])=[CH:19][CH:18]=2)(=[O:15])=[O:16])=[C:4]([Cl:32])[CH:3]=1

Participants

3

Reactant 2

HCID 79341Piperidin-4-olHCID 68492210HCID 68492210, compound

Product 1

HCID 68579796HCID 68579796, compound

Procedure

The title compound was prepared from {4-[2-(4-bromo-2-chloro-phenoxy)-phenylsulfamoyl]-benzoylamino}-acetic acid and 4-hydroxypiperidine according to the method described in Example 1.1/f. MS (EI) 623.3 (MH+).

Sources & evidence

ORD record
ord-128449ff3bce43bdbd0de5eed0135de0
Source dataset
uspto-grants-2013_07
Patent number
US08481527B2

Reaction notes

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