4-(N-Boc-amino)piperidine → N-[2-(4-Amino-piperidin-1-yl)-2-oxo-ethyl]-4-[2-(2,4-dichloro-phenoxy)-phenylsulfamoyl]-benzamide hydrochloride

Participants

Role	Name	HCID	Charge
Reactant	4-(N-Boc-amino)piperidine	HCID 723833	—
Reactant	{4-[2-(2,4-Dichloro-phenoxy)-phenylsulfamoyl]-benzoylamino}-acetic acid	HCID 68493493	—
Product	N-[2-(4-Amino-piperidin-1-yl)-2-oxo-ethyl]-4-[2-(2,4-dichloro-phenoxy)-phenylsulfamoyl]-benzamide hydrochloride	HCID 68577155	—

Reaction Steps

The title compound was prepared from {4-[2-(2,4-dichloro-phenoxy)-phenylsulfamoyl]-benzoylamino}-acetic acid (Example 1.1/e) and piperidin-4-yl-carbamic acid tert-butyl ester (Aldrich) according to the method described in Example 11.1. MS (EI) 577.2 (MH±).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08481527B2
Source dataset	uspto-grants-2013_07
ORD ID	ord-70f63c67f08e4c3789420ea9d591c14d
Source note	uspto-grants-2013_07