HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 1,4-diazepane-1-carboxylate → N-(2-[1,4]Diazepan-1-yl-2-oxo-ethyl)-4-[2-(2,4-dichloro-benzoyl)-phenylsulfamoyl]-benzamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 1,4-diazepane-1-carboxylate | HCID 2756058 | — |
| Reactant | {4-[2-(2,4-Dichloro-benzoyl)-phenylsulfamoyl]-benzoylamino}-acetic acid | HCID 68492509 | — |
| Product | N-(2-[1,4]Diazepan-1-yl-2-oxo-ethyl)-4-[2-(2,4-dichloro-benzoyl)-phenylsulfamoyl]-benzamide hydrochloride | HCID 68579610 | — |
Reaction Steps
The title compound was prepared from {4-[2-(2,4-dichloro-benzoyl)-phenylsulfamoyl]-benzoylamino}-acetic acid (Example 6.1/c)) and [1,4]diazepane-1-carboxylic acid tert-butyl ester (Fluka) according to the method described in Example 11.1. MS (EI) 589.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481527B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-ddffdb00936b4db3939ac70bd4c1bb54 |
| Source note | uspto-grants-2013_07 |