HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → 4-[2-(2,4-Dichloro-benzoyl)-phenylsulfamoyl]-N-(2-oxo-2-piperazin-1-yl-ethyl)-benzamide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | {4-[2-(2,4-Dichloro-benzoyl)-phenylsulfamoyl]-benzoylamino}-acetic acid | HCID 68492509 | — |
| Product | 4-[2-(2,4-Dichloro-benzoyl)-phenylsulfamoyl]-N-(2-oxo-2-piperazin-1-yl-ethyl)-benzamide hydrochloride | HCID 68577385 | — |
Reaction Steps
The title compound was prepared from {4-[2-(2,4-dichloro-benzoyl)-phenylsulfamoyl]-benzoylamino}-acetic acid (Example 6.1/c)) and piperazine-1-carboxylic acid tert-butyl ester (Aldrich) according to the method described in Example 11.1. MS (EI) 575.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481527B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-00a10b6da80444c18b1451866eaf5322 |
| Source note | uspto-grants-2013_07 |