Hydrochloric Acid → HCID 53252097, compound

Participants

Reaction Steps

(S)-tert-butyl 1-(2-(benzo[d]thiazol-2-ylamino)ethylamino)-1-oxo-3-(thiophen-2-yl)propan-2-ylcarbamate (195.9 mg, 0.439 mmol) was suspended in 1,4-dioxane (4 mL) and treated with 4N HCl in 1,4-dioxane (4 mL, 16.0 mmol). The resulting mixture became homogenous, then a solid separated as the stirring continued for 4 h. The solid was collected by filtration, washed with 1,4-dioxane, then dried in a vacuum oven overnight at room temperature, to yield the title compound as its corresponding hydrochloride salt, as a white solid.

Provenance & Evidence