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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 447196Generated: October 29, 2026

(4-Fluoro-3-methylphenyl)boronic acid → 2-Chloro-4-[1-(4-fluoro-3-methyl-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridine

https://huagongshe.com/reaction/447196

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Fluoro-3-methylphenyl)boronic acidHCID 2774580—
ReactantHCID 178418879HCID 178418879—
Product2-Chloro-4-[1-(4-fluoro-3-methyl-phenyl)-2-methyl-1H-imidazol-4-ylethynyl]-pyridineHCID 86595316—

Reaction Steps

The title compound, MS: m/e=326.4 (M+H+), was prepared in accordance with the general method of example 7 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 4-fluoro-3-methyl-benzene boronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481548B2
Source datasetuspto-grants-2013_07
ORD IDord-c73591c8297e4ebeab774438d676f800
Source noteuspto-grants-2013_07