HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 4-(4-Bromophenyl)-1-methylpiperidin-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(4-Bromophenyl)-4-hydroxypiperidine | HCID 93911 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-(4-Bromophenyl)-1-methylpiperidin-4-ol | HCID 10659634 | — |
Reaction Steps
A reaction mixture of 4-(4-bromophenyl)piperidin-4-ol (1.5 g, 5.9 mmol), methyl iodide (0.4 mL, 6.4 mmol), and K2CO3 (1.2 g, 8.8 mmol) in acetone was stirred at rt for 90 min
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481533B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-514688907e8a4efe87421ee0af244f1a |
| Source note | uspto-grants-2013_07 |