HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 53411782, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl 2-(2,3-difluoro-4-nitrophenyl)malonate | HCID 59683248 | — |
| Reactant | Diethyl 2-(2,3-difluoro-6-nitrophenyl)malonate | HCID 68625680 | — |
| Product | HCID 53411782 | HCID 53411782 | — |
Reaction Steps
The mixture of diethyl 2-(2,3-difluoro-4-nitrophenyl)malonate and diethyl 2-(2,3-difluoro-6-nitrophenyl)malonate from D15 (0.5 g) was heated with 11M hydrochloric acid (5 ml) at reflux overnight then evaporated to give 320 mg of the title compound (pale yellow solid) as a 1:1 mixture with 2,3-difluoro-6-nitrophenylacetic acid. M−—CO2H=172.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481566B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-fe19fdc20b0e4130a4e18f7ead39579a |
| Source note | uspto-grants-2013_07 |