Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | 2,3-Difluoro-6-iodo-4-methylbenzenamine | HCID 59683249 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 59683263 | HCID 59683263 | — |
Reaction Steps
A mixture of 2,3-difluoro-6-iodo-4-methylaniline D19 (330 mg, 1.2 mmol), triphosgene (150 mg, 0.5 mmol), and dioxan (5 ml) was heated at 100° C. for 15 min then cooled and evaporated to give the crude title compound used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08481566B2 |
|---|
| Source dataset | uspto-grants-2013_07 |
|---|
| ORD ID | ord-307aeeb95f404af784f8c8b4effde791 |
|---|
| Source note | uspto-grants-2013_07 |
|---|
