HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68624356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59683267 | HCID 59683267 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68624356 | HCID 68624356 | — |
Reaction Steps
1,1-Dimethylethyl 4-(4,5-difluoro-6-methyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-piperidinecarboxylate D22 (150 mg, 0.4 mmol) was dissolved in dichloromethane (5 ml) and treated with HCl in 1,4-dioxane (1 ml×4M) at room temperature for 4 h. Solvent was then evaporated to afford the title compound, 120 mg. M++H=268.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481566B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-d039bc95c8ca488aae0caeb29bebd094 |
| Source note | uspto-grants-2013_07 |