反应详情

温度

5 °C

3.10 g 2-amino-4-phenylthiazole (176 mmol) and 3.00 g benzoylisothiocyanate were heated in 50 ml acetone for 2 hours at reflux, during which a yellow solid was formed. The reaction mixture was subsequently stirred for 30 minutes at 5° C., the solid was suction-isolated and washed multiple times with n-pentane. After drying, 4.20 g of the target structure was obtained as an amorphous yellow solid.

1. temperatureat reflux, during which a yellow solid
2. customwas formed
3. customthe solid was suction-isolated
4. washwashed multiple times with n-pentane
5. customAfter drying
6. custom4.20 g of the target structure was obtained as an amorphous yellow solid