反应详情

To 13.0 g (84.92 mmol) 3-chloro-2-methylanisole in 80 ml CCl4 at reflux were added 0.4 g dibenzoyl peroxide and then, subsequently and portion-wise, a mixture of 15.2 g N-bromosuccinimide and 0.4 g dibenzoyl peroxide. After completion of reaction the mixture was evaporation-concentrated, the residue was dissolved in dichloromethane, was sequentially washed with water and saturated NaCl solution, was dried over MgSO4, was filtered and again evaporation-concentrated. 20.8 yellow oil.

1. customAfter completion of reaction the mixture
2. concentrationwas evaporation-concentrated
3. dissolutionthe residue was dissolved in dichloromethane
4. washwas sequentially washed with water and saturated NaCl solution
5. dry with materialwas dried over MgSO4
6. filtrationwas filtered
7. concentrationagain evaporation-concentrated