反应详情

21a was dissolved in 2.5 mL of DCM and 2.5 mL of TFA was added. The mixture was stirred at room temperature for 2 h then evaporated and the crude material was dissolved in DCM, washed with saturated NaHCO3 (3×10 mL), dried, filtered and evaporated to afford 21b.

1. customthen evaporated
2. dissolutionthe crude material was dissolved in DCM
3. washwashed with saturated NaHCO3 (3×10 mL)
4. customdried
5. filtrationfiltered
6. customevaporated