反应详情

To a mixture of 15.3 g of 3-chloroperbenzoic acid in 270 ml of absolute methylene chloride are added 14.2 g of 2-allyloxyphenylsulfonamide over 2 minutes. The solution is then heated to reflux for 3 hours, cooled, and then washed three times with saturated sodium carbonate solution and once with water. The organic phase is dried and concentrated, affording 11.9 g of 2-oxiranylmethoxyphenylsulfonamide with a melting point of 132°-133° C.

1. temperatureThe solution is then heated
2. temperatureto reflux for 3 hours
3. temperaturecooled
4. washwashed three times with saturated sodium carbonate solution
5. customThe organic phase is dried
6. concentrationconcentrated