Benzamide → HCID 178484329, compound

HRID 44870Notes

Reaction equation

HRID 44870 reaction equation
[C:1]([NH2:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:10][N:11]([CH:13](OC)OC)[CH3:12]>>[CH3:10][N:11](/[CH:13]=[N:9]/[C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH3:12]

Participants

3

Reactant 2

HCID 2331BenzamideHCID 78373Dimethylformamide dimethyl acetal

Product 1

HCID 178484329HCID 178484329, compound

Procedure

A solution of benzamide (1-135) in DMF-DMA was stirred for 3 h at 110° C., then cooled to rt. The solid was collected by filtration, the filter cake washed with PE and air dried to give the desired (E)-N-((dimethylamino)methylene)benzamide (compound II-135).

Workup

  1. filtrationThe solid was collected by filtration
  2. washthe filter cake washed with PE and air
  3. customdried

Sources & evidence

ORD record
ord-60cf9aac5c844cf78fcfd67b247f5f31
Source dataset
uspto-grants-2013_09
Patent number
US08541418B2

Reaction notes

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