HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Bromophenyl)-1H-imidazole → (R)-2-(2-(3-bromophenyl)-1H-imidazol-1-yl)-7-ethyl-8-isopropyl-5-methyl-7,8-dihydropteridin-6(5H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Bromophenyl)-1H-imidazole | HCID 52983884 | — |
| Reactant | (R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropyrimido[4,5-b]pyrazine | HCID 58405561 | — |
| Product | (R)-2-(2-(3-bromophenyl)-1H-imidazol-1-yl)-7-ethyl-8-isopropyl-5-methyl-7,8-dihydropteridin-6(5H)-one | HCID 58405672 | — |
Reaction Steps
The title compound was prepared similarly to the methods described in Example 26, with Intermediate C instead of Intermediate B and with 2-(3-bromophenyl)-1H-imidazole instead of 2-phenyl-1H-imidazole. LCMS: 455.0 m/z (M+H)+; ret. Time: 4.34 min (Analytical Method D).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08541418B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-7342c4922c9a4cf88d354e46cf2a3d9d |
| Source note | uspto-grants-2013_09 |