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0 °C

To a solution of methyl 6-amino-2-naphthoate (0.5 g) in THF (10 ml) was added pyridinium tribromide (0.87 g). The reaction mixture was stirred at 0° C. for 1 h after which it was then filtered through a pad of SiO2 and washed with hexane. The organic washings were evaporated to dryness and the residue was purified by flash chromatography eluting with hexane to afford the titled compound.

1. filtrationwas then filtered through a pad of SiO2
2. washwashed with hexane
3. customThe organic washings were evaporated to dryness
4. customthe residue was purified by flash chromatography
5. washeluting with hexane