Pyrrolidine → HCID 57960883, compound

HRID 449066Notes

Reaction equation

HRID 449066 reaction equation
[CH3:1][N:2]([CH2:4][C@H:5]1[CH2:8][C@H:7]([C:9]2[N:13]3[CH:14]=[CH:15][N:16]=[C:17]([NH2:18])[C:12]3=[C:11]([C:19]3[CH:24]=[CH:23][C:22]([O:25][C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=4)=[CH:21][CH:20]=3)[N:10]=2)[CH2:6]1)[CH3:3].N1CC[CH2:34][CH2:33]1>>[O:25]([C:22]1[CH:21]=[CH:20][C:19]([C:11]2[N:10]=[C:9]([CH:7]3[CH2:6][CH:5]([CH2:4][N:2]4[CH2:1][CH2:34][CH2:33][CH2:3]4)[CH2:8]3)[N:13]3[CH:14]=[CH:15][N:16]=[C:17]([NH2:18])[C:12]=23)=[CH:24][CH:23]=1)[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 178483680HCID 178483680, compound

Product 1

HCID 57960883HCID 57960883, compound

Procedure

Prepared according to the procedure described above for trans-3-(3-dimethylaminomethyl-cyclobutyl)-1-(4-phenoxy-phenyl)-imidazo[1,5-a]pyrazin-8-ylamine, except using pyrrolidine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-489d3add71ff4bb7829816435628af4f
Source dataset
uspto-grants-2013_07
Patent number
US08481733B2

Reaction notes

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