HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22645922, compound → 3,3,4,4-Tetrafluoropyrrolidine Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22645922 | HCID 22645922 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3,3,4,4-Tetrafluoropyrrolidine Hydrochloride | HCID 22645920 | 98% |
Reaction Steps
An ethanol solution of 16.9 g of the residue 3,3,4,4-tetrafluoro-1-benzyl-pyrrolidine hydrochloride and 1.8 g of 10% Pd/C was stirred at room temperature for 3 hours in a manner of contacting hydrogen gas under ordinary pressure. After filtration, the solvent was distilled off to provide 11 g (yield: 98%) of desired 3,3,4,4-tetrafluoro-pyrrolidine hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481774B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-fe29a1d4e88448a695dcedbcf016f3e5 |
| Source note | uspto-grants-2013_07 |