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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 449359Generated: October 29, 2026

Hydrochloric Acid → Hydrochloric Acid

https://huagongshe.com/reaction/449359

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 86645774HCID 86645774—
SolventMethanolHCID 887—
Solvent1,4-DioxaneHCID 31275—
ProductHydrochloric AcidHCID 313—
ProductHCID 28121871HCID 28121871—

Reaction Steps

2 mL of 4 N HCl in 1,4-dioxane was added to a solution of tert-butyl(cis-2-methoxycyclohexyl)carbamate (0.17 g, 0.74 mmol) in methanol (0.5 mL). The reaction mixture was stirred at r.t. overnight. The volatiles were removed under reduced pressure to afford the desired product as HCl salt. Analytic LCMS (M+H)+: m/z=130.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481732B2
Source datasetuspto-grants-2013_07
ORD IDord-ae15371947a641dbb0efb1c65b8afa2e
Source noteuspto-grants-2013_07