反应详情

A mixture of 2-(trans-4-methoxycyclohexyl)-1H-isoindole-1,3(2H)-dione (0.27 g, 1.0 mmol), and hydrazine hydrate (63.3 uL, 0.00130 mol) in ethanol (2.0 mL) was heated at reflux for 1 h. After cooling, the solid was filtered off, and the filtrate was concentrated to yield the desired product (0.12 g, 89%).

1. temperaturewas heated
2. temperatureat reflux for 1 h
3. temperatureAfter cooling
4. filtrationthe solid was filtered off
5. concentrationthe filtrate was concentrated