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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 449365Generated: October 26, 2026

Methyl iodide → (1R,2S)-2-Methoxy-2,3-dihydro-1H-inden-1-amine

https://huagongshe.com/reaction/449365

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium hydrideHCID 24758—
Reactanttert-Butyl ((1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)carbamateHCID 17998891—
Product(1R,2S)-2-Methoxy-2,3-dihydro-1H-inden-1-amineHCID 28109796—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 57, Step 2 starting from tert-butyl[(1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamate, sodium hydride and methyl iodide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481732B2
Source datasetuspto-grants-2013_07
ORD IDord-04762cc6821e4e53a87f0ec03b561b74
Source noteuspto-grants-2013_07