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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 449373Generated: October 29, 2026

1246210-02-5 → HCID 49779588, compound

https://huagongshe.com/reaction/449373

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1246210-02-5HCID 59496539—
Reactant4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl saltHCID 67541489—
ProductHCID 49779588HCID 49779588—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 5 starting from 1,1-difluoro-4-isocyanatocyclohexane and 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt. Analytic LCMS (M+H)+: m/z=486.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481732B2
Source datasetuspto-grants-2013_07
ORD IDord-61869f62c1094ea3b85dea4d844be750
Source noteuspto-grants-2013_07