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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 449374Generated: October 30, 2026

HCID 19985489, compound → HCID 59496633, compound

https://huagongshe.com/reaction/449374

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 19985489HCID 19985489—
Reactant4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl saltHCID 67541489—
ProductHCID 59496633HCID 59496633—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 5 starting from 1-isocyanato-4-(trifluoromethyl)cyclohexane, and 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt. Analytic LCMS (M+H)+: m/z=518.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481732B2
Source datasetuspto-grants-2013_07
ORD IDord-91bfb64053c6465193cab521445f4fd9
Source noteuspto-grants-2013_07