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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 449375Generated: October 30, 2026

4-Fluorophenylacetyl chloride → HCID 67541782, compound

https://huagongshe.com/reaction/449375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorophenylacetyl chlorideHCID 3744988—
Reactant4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl saltHCID 67541489—
ProductHCID 67541782HCID 67541782—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 2 starting from (4-fluorophenyl)acetyl chloride (Aldrich, Cat. #466956) and 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt. Analytic LCMS (M+H)+: m/z=461.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481732B2
Source datasetuspto-grants-2013_07
ORD IDord-3d36c34cb5d148c39a6bdad835615556
Source noteuspto-grants-2013_07