HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → HCID 59496724, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | N-Methylcyclohexylamine | HCID 7514 | — |
| Reactant | 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt | HCID 67541489 | — |
| Product | HCID 59496724 | HCID 59496724 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 40 starting from N-methylcyclohexanamine (Aldrich, Cat. #103322), phosgene and 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt. Analytic LCMS (M+H)+: m/z=464.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481732B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-826e1fa598804e3db49b883cadbaf9c6 |
| Source note | uspto-grants-2013_07 |