HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → HCID 49779701, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | (1R,2S)-(+)-cis-1-Amino-2-indanol | HCID 2725045 | — |
| Reactant | 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt | HCID 67541489 | — |
| Product | HCID 49779701 | HCID 49779701 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 42 starting from phosgene, 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt and (1R,2S)-1-aminoindan-2-ol. Analytic LCMS (M+H)+: m/z=500.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481732B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-a5e73383bf8e4e86a2d14860a7528c32 |
| Source note | uspto-grants-2013_07 |