HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → HCID 49779702, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt | HCID 67541489 | — |
| Product | HCID 49779702 | HCID 49779702 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 40 starting from 1,3-thiazol-2-amine (Aldrich, Cat. #123129), phosgene and 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt. Analytic LCMS (M+H)+: m/z=451.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08481732B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-2f0e1db15b5546a896b9f6a690d3ddfc |
| Source note | uspto-grants-2013_07 |