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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 449445Generated: November 4, 2026

1-Isocyanato-1-(trifluoromethyl)cyclopropane → HCID 49779903, compound

https://huagongshe.com/reaction/449445

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Isocyanato-1-(trifluoromethyl)cyclopropaneHCID 58920817—
Reactant4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl saltHCID 67541489—
ProductHCID 49779903HCID 49779903—

Reaction Steps

This compound was prepared by using procedures analogous to those described for the synthesis of Example 5 starting from 1-isocyanato-1-(trifluoromethyl)cyclopropane, and 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt. Analytic LCMS (M+H)+: m/z=476.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08481732B2
Source datasetuspto-grants-2013_07
ORD IDord-c50a74b7f0f54b0489e744f6d0ea6359
Source noteuspto-grants-2013_07