Hydrochloric Acid → Hydrochloric Acid

Participants

Reaction Steps

The tert-butyl 7-(3-cyanobenzyloxy)-1,2,3,4-tetrahydronaphthalen-1-ylcarbamate (0.045 g) was taken up in 4 M HCl in dioxane (2 mL) at r.t. After stirring for 2 h. the reaction was concentrated under reduced pressure to give a residue. This residue was taken up in acetonitrile and reconcentrated under reduced pressure two times to give crude 3-{[(8-amino-5,6,7,8-tetrahydronaphthalen-2-yl)oxy]methyl}benzonitrile as HCl salt (0.035 g) as a solid residue.

Provenance & Evidence