HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2,6-Dichloro-4-(dimethylcarbamoyl)benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,6-Dichloro-4-(dimethylcarbamoyl)benzoic acid | HCID 67128887 | — |
| Product | 2,6-Dichloro-4-(dimethylcarbamoyl)benzoyl chloride | HCID 86648962 | 100% |
Reaction Steps
A solution of 2,6-dichloro-4-(dimethylcarbamoyl)benzoic acid (65 mg, 0.21 mmol) in SOCl2 (3 mL) was heated to reflux for overnight and then cooled to room temperature. The mixture was concentrated under reduced pressure to give crude 2,6-dichloro-4-(dimethylcarbamoyl)benzoyl chloride (70 mg, yield: 100%), which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486950B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-4d307f5cca2e408dab15fb76c86b15f4 |
| Source note | uspto-grants-2013_07 |