反应详情

Thionyl chloride (10 ml) was added to 4-aminobenzoic acid (1.0 g, 7.29 mmol) and the solution was heated to reflux for 16 hr. Thionyl chloride was removed under vacuum to yield 4-amino-benzoyl chloride (1.13 g, 100%).

1. temperaturethe solution was heated
2. temperatureto reflux for 16 hr
3. customThionyl chloride was removed under vacuum