HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 62005685, compound → HCID 53402843, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 62005685 | HCID 62005685 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 53402843 | HCID 53402843 | 72.2% |
Reaction Steps
A solution of 1-(4-nitro-phenyl)-pyrrolidine-2-carboxylic acid methyl ester (0.55 g, 2.2 mmol) in methanol (15 ml) was hydrogenated over 10% Pd—C (50 mg) at 30 psi until no further gas uptake was observed. The reaction mixture was then filtered over celite and the filtrate evaporated to yield 1-(4-amino-phenyl)-pyrrolidine-2-carboxylic acid methyl ester (0.35 g, 72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486962B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-f56950bbdb1b484bb050eecc3fc93d8d |
| Source note | uspto-grants-2013_07 |