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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 450071Generated: October 29, 2026

HCID 62005685, compound → HCID 53402843, compound

https://huagongshe.com/reaction/450071

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 62005685HCID 62005685—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 53402843HCID 5340284372.2%

Reaction Steps

A solution of 1-(4-nitro-phenyl)-pyrrolidine-2-carboxylic acid methyl ester (0.55 g, 2.2 mmol) in methanol (15 ml) was hydrogenated over 10% Pd—C (50 mg) at 30 psi until no further gas uptake was observed. The reaction mixture was then filtered over celite and the filtrate evaporated to yield 1-(4-amino-phenyl)-pyrrolidine-2-carboxylic acid methyl ester (0.35 g, 72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08486962B2
Source datasetuspto-grants-2013_07
ORD IDord-f56950bbdb1b484bb050eecc3fc93d8d
Source noteuspto-grants-2013_07