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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 450111Generated: October 30, 2026

Hydrochloric Acid → HCID 67172481, compound

https://huagongshe.com/reaction/450111

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 67172047HCID 67172047—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 67172481HCID 67172481—

Reaction Steps

To tert-butyl 1-(1H-pyrrolo[2,3-b]pyridin-3-yl)-3-azabicyclo[3.1.0]hexane-3-carboxylate (100 mg, 0.3 mmol) in dioxan (3 ml) was added 1 mL of a 4M solution of HCl in dioxan. The reaction mixture was stirred at RT for 12 h and concentrated to dryness to afford the title compound as a buff colored solid (60 mg), which was used immediately in the following step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08486964B2
Source datasetuspto-grants-2013_07
ORD IDord-c4bafe7ad8674c308292aa6751d2fa3a
Source noteuspto-grants-2013_07