HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67172481, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 67172047 | HCID 67172047 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67172481 | HCID 67172481 | — |
Reaction Steps
To tert-butyl 1-(1H-pyrrolo[2,3-b]pyridin-3-yl)-3-azabicyclo[3.1.0]hexane-3-carboxylate (100 mg, 0.3 mmol) in dioxan (3 ml) was added 1 mL of a 4M solution of HCl in dioxan. The reaction mixture was stirred at RT for 12 h and concentrated to dryness to afford the title compound as a buff colored solid (60 mg), which was used immediately in the following step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486964B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-c4bafe7ad8674c308292aa6751d2fa3a |
| Source note | uspto-grants-2013_07 |