HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 68734950, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 1H-Pyrazol-3-amine, 5-methyl- | HCID 93146 | — |
| Reactant | 2,3,6-Trifluoro-5-nitropyridine | HCID 67455421 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68734950 | HCID 68734950 | — |
Reaction Steps
To a solution of 2,3,6-trifluoro-5-nitropyridine (Intermediate 40, 1.0 g) in EtOH (20 ml) at 0° C., was added 5-methyl-1H-pyrazol-3-amine (550 mg) and DIPEA (2 ml). The resulting mixture was stirred at this temperature overnight. The title compound was collected via filtration (780 mg). LCMS: 377 [M+1].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486966B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-402068d2d797455684e34222d785e0e8 |
| Source note | uspto-grants-2013_07 |