HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate → Methyl 4-(4-fluoro-2-isopropoxyphenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-chloro-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate | HCID 2759834 | — |
| Reactant | 4-Fluoro-2-(1-methylethoxy)benzenamine | HCID 3756385 | — |
| Product | Methyl 4-(4-fluoro-2-isopropoxyphenylamino)-5-methyl-thieno[2,3-d]pyrimidine-6-carboxylate | HCID 46182043 | — |
Reaction Steps
Prepared from 4-fluoro-2-iso-propoxyaniline and methyl 4-chloro-5-methylthieno[2,3-d]pyrimidine-6-carboxylate in an analogous fashion to that given in general route 1. Yield (0.25 g, 53%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08486953B2 |
| Source dataset | uspto-grants-2013_07 |
| ORD ID | ord-07f3395e795c4d0d85d7ee056ed2b902 |
| Source note | uspto-grants-2013_07 |