Ammonia → N-Hydroxy-4-pyridazinecarboximidamide

HRID 450659Notes

Reaction equation

HRID 450659 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]#N)=[CH:3][N:2]=1.[NH2:9][OH:10].[NH3:11]>>[OH:10][N:9]=[C:7]([C:4]1[CH:5]=[CH:6][N:1]=[N:2][CH:3]=1)[NH2:11]

Participants

4

Reactant 3

HCID 222AmmoniaHCID 787HydroxylamineHCID 15781246Pyridazine-4-carbonitrile

Product 1

HCID 136140373N-Hydroxy-4-pyridazinecarboximidamide

Procedure

The title compound was prepared according to the procedure of Example 79C using the product of Example 83C and hydroxylamine (Aldrich). 1H NMR (300 MHz, DMSO-d6) δ 6.19 (s, 2 H), 7.87 (dd, J=5.4, 2.4 Hz, 1 H), 9.25 (dd, J=5.4, 1.4 Hz, 1 H), 9.46 (dd, J=2.4, 1.4 Hz, 1 H), 10.36 (s, 1 H) ppm; MS (DCI/NH3) m/z 139 (M+H)+, 156 (M+NH4)+.

Sources & evidence

ORD record
ord-d5c28239f28f4c78905e13d0b07079ba
Source dataset
uspto-grants-2013_07
Patent number
US08486979B2

Reaction notes

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