Ammonia → HCID 67026321, compound

HRID 450699Notes

Reaction equation

HRID 450699 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][CH:12]=1)[C:6](=[N:8][OH:9])[NH2:7])#[N:2].[Br:13][C:14]1[CH:15]=[N:16][CH:17]=[C:18]([CH:22]=1)[C:19](Cl)=O.N>>[Br:13][C:14]1[CH:22]=[C:18]([C:19]2[O:9][N:8]=[C:6]([C:5]3[CH:4]=[C:3]([CH:12]=[CH:11][CH:10]=3)[C:1]#[N:2])[N:7]=2)[CH:17]=[N:16][CH:15]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 27812235-Bromonicotinoyl chlorideHCID 573689333-Cyano-N-hydroxy-benzamidine

Product 1

HCID 67026321HCID 67026321, compound

Procedure

The title compound was prepared according to the procedure of Example 4B using 3-cyano-N′-hydroxybenzimidamide and 5-bromonicotinoyl chloride (Alfa). 1H NMR (300 MHz, DMSO-d6) δ 7.67 (m, 1 H), 7.74 (m, 1 H), 8.41 (m, 1 H), 8.49 (m, 1 H), 8.64 (s, 1 H), 8.93 (s, 1 H), 9.4 (s, 1 H) ppm; MS (DCI/NH3) m/z 327 (M+H)+.

Sources & evidence

ORD record
ord-97105b0ef5db46c890f1340146560630
Source dataset
uspto-grants-2013_07
Patent number
US08486979B2

Reaction notes

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